Losing the Weight Loss Meds

A 10-Week Playbook for Stopping GLP-1 Medications Without Regaining the Weight

Most people regain weight after weight loss medications. You don’t have to.

New weight loss medications like Ozempic®, Wegovy®, Mounjaro®, and Zepbound® (known as GLP-1s) can help you lose weight, but research shows that without a plan, the weight almost always comes back if the prescription ends. Losing the Weight Loss Meds is the first playbook designed specifically to help you transition off medication—and keep your hard-earned success for life.

Written by leading obesity experts Dr. Holly R. Wyatt and Dr. James O. Hill, Losing the Weight Loss Meds lays out a science-backed, 10-week program to replace medication with the power of food, physical activity, and mindstate. You’ll discover how to:

• Reset your appetite naturally with smart food strategies
• Use physical activity to restore and optimize metabolism
• Strengthen your mindstate to build resilience against cravings and setbacks
• Catch early signs of weight regain and stop it before it snowballs
• Create routines and environments that make success easier to sustain

This isn’t another quick-fix diet. It’s a practical guide for the moment millions of people now face: life after GLP-1s.

Whether you’re preparing to stop medication now or later, or just beginning your weight loss journey, this playbook equips you with the tools to protect your progress and fully live the life you’ve worked so hard to create.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2025 by Holly R. Wyatt, MD and James O. Hill, PhD. (P)2025 Brilliance Publishing, Inc., all rights reserved.

Same old diet advice

Zepbound has been life changing for me. It helped finally end 40 years of roller coaster dieting, where I would successfully lose the weight, and then struggle to keep it off over and over again. Zepbound quiets the incessant food noise, helps me make excellent food choices, skip the sweets, and because I am thin and healthy now, I am motivated to run three times/week and lift three times/week consistently. Zepbound is a weight MAINTENANCE medication. That's the whole point. If Wyatt's diet advice worked, I wouldn't need Zepbound. My advice: if Zepbound works for you, do everything you can to stay on it.