What actually causes cognitive decline, and how much of it can we do something about?

In this episode, Michael talks with neurologist and neuroscientist Dr. Majid Fotuhi about dementia, Alzheimer’s, memory loss, and the everyday habits that shape brain health over time. They discuss why Alzheimer’s is only part of the story, why some people remain mentally sharp into old age, and what the evidence says about exercise, sleep, diet, stress, and cognitive activity.

They also cover ADHD, attention, brain training, and the difference between ordinary forgetfulness and something more serious.

At the center of it all is a simple but important idea: many people think cognitive decline is just an unavoidable part of aging, when in fact there is often more room to protect brain function than most of us realize.

Majid Fotuhi, MD, PhD, is an adjunct professor of Neuroscience at Johns Hopkins’s Mind/Brain Institute, an adjunct professor of Psychological and Brain Sciences at George Washington University, and is the medical director of NeuroGrow Brain Fitness Center. His groundbreaking, proprietary research has been published in The Lancet, Nature, Neurology, Neuron, Proceedings of National Academy of Science, the Journal of Prevention of Alzheimer’s Disease, Journal of Rehabilitation, and Journal of Alzheimer’s Disease Reports, among others. His new book is The Invincible Brain: The Clinically Proven Plan to Age-Proof Your Brain and Stay Sharp for Life.

Why does religion still dominate American politics when so many other wealthy democracies secularized long ago?

In this episode, Michael Shermer talks with historian Matthew Avery Sutton about the long relationship between Christianity and American power. From the Puritans to Lincoln, from the Scopes trial to the Religious Right, from slavery to same-sex marriage, this conversation tracks how religious belief has shaped the country, and how politics keeps reshaping religion in return.

Matthew Avery Sutton is the Claudius O. and Mary Johnson Distinguished Professor and chair of the Department of History at Washington State University. His new book is Chosen Land: How Christianity Made America and Americans Remade Christianity.

How does something living emerge from something that isn’t?

In this episode, Lee Cronin pushes the question back even further: before cells, before DNA, before biology as we usually think of it, what kind of process could make matter start organizing itself into something alive?

He and Michael Shermer get into assembly theory, RNA, autocatalysis, and the deeper puzzle of whether causation and selection may already be at work long before the first organism appears. The conversation also branches into consciousness, free will, and the possibility that life may be widespread in the universe, even if it looks nothing like life on Earth.

Lee Cronin is Regius Professor of Chemistry at the University of Glasgow, Scotland, where he leads one of the world’s largest multidisciplinary chemistry research groups. He has raised more than $35 million in grant funding, with current research income of $15 million, and has authored more than 350 peer-reviewed papers, including recent work published in Nature, Science, and PNAS. He and his team are trying to make artificial life forms, find alien life, explore the digitization of chemistry, understand how information can be encoded into chemicals and construct chemical computers.

On Easter Sunday, Michael asks whether the resurrection should be understood as history, myth, or something deeper.

Fewer people are having sex, fewer are forming lasting relationships, and many feel more isolated than ever. Why?

Michael Shermer sits down with neuroscientist and author Debra Soh to discuss her new book Sextinction: The Decline of Sex and the Future of Intimacy. They talk about the so-called sex recession, why modern dating feels so broken, and how social media, pornography, AI companions, and changing expectations between men and women are reshaping intimacy.

The discussion also touches on Gen Z mental health, dating apps, the manosphere, marriage, and the broader social consequences of a culture that increasingly substitutes screens for real human connection.

Debra Soh is a neuroscientist who specializes in human sexuality and biological explanations for behavior. She received her PhD from York University in Toronto and worked as a scientific researcher for eleven years. As a journalist, Soh writes about technology, health, and the politicization of science.

What do gaslighting, bullying, cults, and coercion have in common? In this episode, Michael Shermer speaks with Jennifer Fraser about the psychology and neuroscience of manipulation, the recurring structure of abuse cultures, and the way authority can distort perception. Their discussion looks at fear, humiliation, retaliation, favoritism, empathy deficits, and the warning signs that distinguish legitimate leadership from coercive control across schools, workplaces, sports, relationships, and institutions.

Jennifer Fraser is the author of four books and an international expert on bullying and abuse. Her latest book is The Gaslit Brain: Protect Your Brain from the Lies of Bullying, Gaslighting, and Institutional Complicity.

How much of what we call “basic morality” is actually inherited from Christianity? Bart Ehrman joins Michael Shermer for a wide-ranging conversation about one of the biggest moral questions in history: why do we feel obligated to care for strangers at all?

Drawing from his new book Love Thy Stranger, Ehrman argues that the idea of helping people outside your tribe, family, or nation was not a moral given in the ancient world. Greek and Roman ethics made room for loyalty, friendship, and civic duty, but not for radical concern for the outsider. He makes the case that Jesus changed that moral equation—and that his teachings still shape the modern West, including many people who no longer consider themselves religious.

The conversation also covers Ehrman’s own path from evangelical Christianity to agnostic atheism, the problem of suffering, whether pure altruism really exists, and the difference between forgiveness and atonement.

Bart Ehrman is the James A. Gray Distinguished Professor of Religious Studies at the University of North Carolina, Chapel Hill, and The New York Times bestselling author of Misquoting Jesus and How Jesus Became God. His new book is Love Thy Stranger: How Jesus Transformed Our Moral Conscience.

Michael Shermer sits down with novelist and essayist Lionel Shriver for a wide-ranging conversation about what happens when old political labels stop making sense. Shriver reflects on the strange moral and political confusions that now shape debates over immigration, identity, religion, and the meaning of tolerance.

They discuss why immigration has become, in Shriver’s view, the central political issue of this century; why support for illiberal ideas is often framed as compassion; why the culture of fiction and publishing has grown more timid; and how writers can still engage seriously with divisive subjects without surrendering either honesty or nuance.

The conversation also turns personal: Shriver’s religious upbringing, her own personal experiences with immigration, and reflections on the diminishing cultural authority of the novelist.

Lionel Shriver is an author and journalist, a graduate of Columbia University, and a columnist for The Spectator. Her fiction confronts some of the defining issues of modern life: school shootings in We Need to Talk About Kevin, the cost of healthcare in So Much for That, economic instability in The Mandibles, aging and suicide in Should We Stay or Should We Go, and low intelligence and DEI in Mania. Her latest novel, A Better Life, takes up immigration from the perspective of the host.