Episode 2: Knee Edition — Vol. 1, Issue 1

Today's knee edition covers six important studies addressing perioperative protocols and complications. We examine whether systemic corticosteroids improve early TKA recovery, analyze concerning complication patterns with gabapentinoid use, review the underrecognized problem of noise-induced hearing loss in orthopaedic surgery, investigate differential graft failure rates with vancomycin-soaked ACL grafts, evaluate the cost-effectiveness of liposomal bupivacaine for regional anesthesia, and explore predictive models for early postoperative pain in enhanced recovery protocols.

1. "Systemic Low Dose Corticosteroid Improves Early Postoperative Knee Function and Pain Intensity in Patients Undergoing Unilateral Total Knee Arthroplasty: A Blinded Controlled Randomized Clinical Trial" — Ebrahimzadeh MH et al., JB JS Open Access — https://doi.org/10.2106/JBJS.OA.25.00331
2. "Perioperative gabapentinoid use during total knee arthroplasty is associated with higher rates of postoperative complications compared to no use" — Hilo AK et al., Orthop Rev (Pavia) — https://doi.org/10.52965/001c.158288
3. "Noise Levels and Noise-Induced Hearing Loss in the Orthopaedic Operating Room: A Systematic Review" — Powell CJ et al., JB JS Open Access — https://doi.org/10.2106/JBJS.OA.25.00276
4. "Vancomycin-Soaked Quadriceps Tendon Autografts but Not Hamstring Tendon Autografts Are Associated with Early Graft Failure (Graft Resorption) After Primary Anterior Cruciate Ligament Reconstruction: A Single-Center Experience" — Weninger P et al., Indian J Orthop — https://doi.org/10.1007/s43465-025-01632-x
5. "Liposomal Bupivacaine for Adductor Canal Block Combined with IPACK Block in Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial" — Yuan Q et al., Drug Des Devel Ther — https://doi.org/10.2147/DDDT.S566411
6. "Early Postoperative Pain and Its Risk Factors in Patients Undergoing Total Knee Arthroplasty Under the ERAS Protocol" — Wu L et al., J Pain Res — https://doi.org/10.2147/JPR.S549841