Empire of Pain Audiobook By Patrick Radden Keefe cover art

Empire of Pain

The Secret History of the Sackler Dynasty, winner of the Baillie Gifford Prize for Non-Fiction

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Empire of Pain

By: Patrick Radden Keefe
Narrated by: Patrick Radden Keefe
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The gripping and shocking story of three generations of the Sackler family and their roles in the stories of Valium, OxyContin and the opioid crisis. The inspiration behind the Netflix series Painkiller, starring Uzo Aduba and Matthew Broderick. Read by the author, Patrick Radden Keefe.

Winner of the Baillie Gifford Prize for Non-Fiction
A BBC Radio 4 'Book of the Week'

Shortlisted for the Financial Times/McKinsey Business Book of the Year Award
Shortlisted for the Crime Writers' Association Gold Dagger for Non-Fiction
One of Barack Obama’s Favorite Books


The Sackler name adorns the walls of many storied institutions – Harvard; the Metropolitan Museum of Art; Oxford; the Louvre. They are one of the richest families in the world, known for their lavish donations in the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing Oxycontin, a blockbuster painkiller that was a catalyst for the opioid crisis – an international epidemic of drug addiction which has killed nearly half a million people.

In this masterpiece of narrative reporting and writing, award-winning journalist and host of the Wind of Change podcast Patrick Radden Keefe exhaustively documents the jaw-dropping and ferociously compelling reality. Empire of Pain is the story of a dynasty: a parable of twenty-first-century greed.

‘You feel almost guilty for enjoying it so much’ – The Times

Accolades & Awards

Goodreads Choice Award
2021
Business Entertainment & Celebrities Goodreads Choice Award Medical Professionals & Academics Thought-Provoking True Crime Biographies & Memoirs

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Critic reviews

There are so many "they did what?" moments in this book, when your jaw practically hits the page
This is no dense medical tome, but a page-turner with a villainous family to rival the Roys in Succession, and one where every chapter ends with the perfect bombshell.
The story of the Sacklers and OxyContin is a parable of the modern era of philanthropy being deployed to burnish the reputations of financiers and entrepreneurs . . . [A] tour-de-force
Put simply, this book will make your blood boil . . . a devastating portrait of a family consumed by greed and unwilling to take the slightest responsibility or show the least sympathy for what it wrought . . . a highly readable and disturbing narrative. (John Carreyrou, author of Bad Blood)
An engrossing (and frequently enraging) tale of striving, secrecy and self-delusion . . . Even when detailing the most sordid episodes, Keefe’s narrative voice is calm and admirably restrained, allowing his prodigious reporting to speak for itself. His portrait of the family is all the more damning for its stark lucidity. (Jennifer Szalai)
A true tragedy in multiple acts. It is the story of a family that lost its moorings and its morals . . . Written with novelistic family-dynasty and family-dynamic sweep, Empire of Pain is a pharmaceutical Forsythe Saga, a book that in its way is addictive, with a page-turning forward momentum. (David M. Shribman)
Explosive . . . Keefe marshals a large pile of evidence and deploys it with prosecutorial precision . . . Keefe is a gifted storyteller who excels at capturing personalities.
An air-tight indictment of the family behind the opioid crisis . . . [an] impressive exposé (Harriet Ryan)
A damning portrait of the Sacklers, the billionaire clan behind the OxyContin epidemic . . . [Keefe] has a knack for crafting lucid, readable descriptions of the sort of arcane business arrangements the Sacklers favored. (Laura Miller)
Keefe has a way of making the inaccessible incredibly digestible, of morphing complex stories into page-turning thrillers, and he's done it again with Empire of Pain . . . A scathing — but meticulously reported — takedown of the extended family behind OxyContin. It's equal parts juicy society gossip and historical record of how they built their dynasty and eventually pushed Oxy onto the market. (Seija Rankin)
Brilliant Research • Compelling Narrative • Insightful Investigation • Fascinating Story • Important Exposure

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Very good listen. Leaves one wondering about many things. Marketing, real justice vs legal mumble jumbo and greed especially.

Enlightening and disheartening

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Harrowing, horrific, compelling and riveting. Brilliant writing and narration. Highly recommend Empire of Pain.

Empire of Pain

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I read a brief review of this book which stated that the reader had felt guilty at how much they were enjoying the book: it's a great comment and one I can totally endorse. The subject matter, the Sackler family and the total disregard they exhibited in their pursuit of wealth as they lied and pushed their pharmaceutical opiates was stunning.
A brilliantly researched and written narrative non-fiction , expertly read by Patrick Raddon Keele, and most highly recommended

"Addicted to money."

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I cannot even fathom how hard it must have been to write this epic work. the depth of research and detail is staggering. my only disappointment was the ending insofar as there isn't one - they remain criminals at large with the means to exploit the system to their will so they can never be brought to justice. disheartening, yet a story that must be told all the same. thank you.

spectacular work of research

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Brilliant! Needs to be shared on more platforms! Some Sackler descendant/movie producer must be interested...

HBO?Netflix?Award-winning movie/limitedseries?

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