Most skincare advice is focused on fixing what you can see—wrinkles, texture, tone. But by the time those changes appear, the underlying biology has already been shifting for years.

In this episode of The One Thing Podcast, Dr. Rinde sits down with pharmacist and founder of Atika Wellness , Lily Shapiro, PharmD – to explore a more accurate way to think about skin health—one that moves beyond “anti-aging” and toward what she calls skin span.

Lily breaks down the science behind how skin actually ages and why many popular solutions fall short. From the truth about collagen and biotin to the limitations of topical products, this conversation challenges some of the most common assumptions in the skincare world.

You’ll also learn the four core drivers of skin longevity—collagen integrity, antioxidant balance, lipid barrier function, and mitochondrial health—and how a systems-based approach can support your skin from the inside out.

If you’re looking for a clearer, more science-backed way to approach your skin and your health, this episode will give you a new framework to work from.

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Topics covered:
• Why “anti-aging” is the wrong framework
• The truth about collagen, biotin, and hyaluronic acid
• The CALM framework for skin longevity
• How hormones impact skin, especially in midlife
• Why most supplements fall short
• The connection between internal health and visible skin changes

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Follow Dr. Rinde for more conversations focused on the one thing that truly moves your health forward.

Show links: https://www.atikawellness.com/

About our guest:

About Lily Shapiro, PharmD

Lily Shapiro is a pharmacist and the founder of ATIKA, a nutritional dermatology brand built on scientific clarity, therapeutic dosing, and a commitment to skin longevity. Her work centers on helping women nourish the biological foundations of resilient, healthy skin through evidence-based daily nutrition.

During her 40s, Lily began noticing the early signs of collagen decline, dryness, and barrier changes that accompany midlife transitions. What she found in the supplement aisle were under-dosed blends, fragmented routines, and marketing-driven formulations that lacked clinical integrity.

As a pharmacist trained in pharmacology, nutrient metabolism, and compounding, she saw an opportunity to bring therapeutic precision into the ingestible beauty space. ATIKA was created to offer one clinically aligned, properly dosed formula supporting the four core pillars of skin health: collagen structure, lipid barrier integrity, antioxidant defense, and cellular renewal.

• Evidence before trend. Every ingredient is selected based on published human data, not aesthetics or hype.
• Therapeutic dosing. Clinical outcomes require clinical amounts — not pixie-dust blends or proprietary dilution.
• Mechanism-first formulation. Collagen synthesis, barrier lipids, oxidative stress, and cellular energy work together; the formula must reflect that integration.
• Restraint and transparency. No exaggeration, no over-claiming, no clutter — only what is necessary and clinically relevant.

• Doctor of Pharmacy (PharmD)
• Clinical background in compounding and women's health
• Experience analyzing ingredient pharmacokinetics, nutrient pathways, and therapeutic dosing
• Founder & Formulator of ATIKA Advanced Skin Nutrition

Her work reflects a belief that skin longevity begins with foundational biology — collagen structure, barrier lipids, detoxification of oxidative stress, and cellular energy. ATIKA exists to bring these truths to the center of daily ritual.

Why Some Patients Do Everything Right — and Still Don’t Fully Heal

Some patients do everything right — and still don’t fully heal.

They follow the plan. Change their diet. Take the supplements. Commit to lifestyle shifts. Show up consistently. And yet something deeper remains unresolved.

After more than twenty years in clinical practice, Dr. Adam Rinde has seen this pattern repeatedly. At some point, the question shifts from “What are we missing physically?” to “Is there another layer of healing we’re not addressing?”

In this episode of The One Thing Podcast, Dr. Rinde sits down with Eva Müller , an energy practitioner who works in the realm of emotional clearing and consciousness-based healing. Eva believes that unresolved emotional patterns, stored trauma, accumulated stress, and even ancestral influences may contribute to chronic illness in ways we don’t always measure — but still experience.

This conversation is not anti-medicine.

It’s an exploration of whether physical and energetic healing can work in parallel.

• Why some patients hit a healing plateau
• Emotional trauma and stored stress in the body
• The concept of energetic root causes
• Surrender vs. striving in chronic illness
• Why groundedness matters in spiritual work
• How energy-based practices can complement conventional care

Eva Müller is an energy practitioner and meditation guide who works with high-vibrational energetic transmissions to support emotional clearing and expanded awareness. After leaving a traditional career path that felt misaligned, she underwent years of personal transformation that led her into energy-based healing work. Today, she offers live group meditations, small-group healing sessions, and an online platform designed to support deeper emotional and energetic shifts.

Website & Offerings: https://em-healing.com
Free Weekly Live Meditation (Thursdays)

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If you’ve felt like something deeper needs to shift in your healing journey, this episode may expand your framework.

Subscribe to The One Thing Podcast for conversations at the intersection of medicine, resilience, and deeper healing.

What if inflammation isn’t just something to manage… but something you could actually remove?

For decades, chronic inflammation has been treated with suppression — steroids, biologics, immune blockers. But what if there were a way to physically remove inflammatory burden from the bloodstream?

In this episode, we sit down with Dr. Pamela Smith — ER physician, toxicologist, hormone specialist, and pioneer in therapeutic plasma exchange (TPE) — to explore the emerging science behind physically reducing inflammatory load.

We break down:

• What actually happens during therapeutic plasma exchange• How inflammation, cytokines, and antigen load circulate in the blood• Why autoimmune disease may be driven by persistent toxin burden• The connection between mold, plastics, metals, and immune dysfunction• Whether TPE can help long COVID, PCOS, cardiovascular disease, and cognitive decline• Who should — and shouldn’t — consider this therapy

This is not a hype episode.It’s a grounded, nuanced exploration of what’s possible when inflammation is treated as something measurable — and potentially removable.

If you’re navigating autoimmune disease, chronic illness, hormone resistance, long COVID, or simply want to understand the future of inflammation science, this conversation will challenge how you think about immune regulation.

Is therapeutic plasma exchange the next frontier in functional medicine — or an emerging tool still finding its evidence base?

Let’s explore the science.

Dr. Anna Sitkoff, naturopathic physician and medicinal mushroom researcher, reveals why so many people try high-quality mushroom products and feel nothing. This deep dive explores extraction methods, fruiting body versus mycelium, proper dosing, and the clinical applications of Lion's Mane, Cordyceps, Reishi, and Turkey Tail for immune support, gut-brain health, and neurodegeneration.find her on your socials at:@drannasitkoff @lucidummedicinalsfull episode notes at https://onethingpod.com/sitkoff

Dr. Lara Briden challenges everything you think you know about metabolism, revealing why energy—not weight—is the true marker of metabolic health. This conversation explores how modern life has pushed our physiology into states it was never designed for, and offers a compassionate, science-based approach to understanding your body as a logical system rather than a problem to fix.

GUEST INFORMATION:

• Name: Dr. Lara Briden
• Title/Credentials: Naturopathic doctor, author, former evolutionary biology researcher
• Background: Has peer-reviewed publications and thesis in evolutionary biology, specializes in women's health with focus on centering female physiology as normal mammalian function

EPISODE HIGHLIGHTS:

• Evolutionary Biology Framework

• • Dr. Briden explains how her background in evolutionary biology informs her medical practice, viewing women's bodies as logical systems that make biological sense

• Menopause as Evolutionary Advantage

• • Discussion of how menopause evolved as a survival advantage, with post-reproductive women being essential for family group survival

• Debunking the Willpower Myth

• • Challenges the narrative that metabolic issues are about eating too much and exercising too little

• The Asthma Analogy

• • Explains why telling people to "just lose weight" is like telling someone with asthma to "just breathe better"

• Environmental Factors

• • Details how environmental toxins, gut microbiome changes, and epigenetics contribute to metabolic dysfunction across species and generations

• Energy as Metabolic Marker

• • Explains metabolic flexibility and how the body should preferentially burn fat in fasting states

• Blood Sugar Crashes

• • Discusses how insulin resistance often presents as reactive hypoglycemia rather than high blood sugar

• Seed Oils Discussion

• • Dr. Briden shares her perspective on high-dose omega-6 oils as metabolically problematic signaling molecules

• Nervous System and Metabolism

• • Explores how the autonomic nervous system significantly impacts insulin sensitivity and metabolic rate

• Key Metabolic Nutrients

• • Discuss essential nutrients for metabolic health: magnesium, taurine, choline, inositol, and glycine, historically obtained from organ meats

• 
  

• Mitochondria as Masters

• • Fascinating discussion of mitochondria as dynamic cellular powerhouses affected by emotions and social activity

• Lab Testing Simplified

• • Provides practical lab markers for insulin resistance: ALT levels, ALT to AST ratio, and triglycerides

  RESOURCES MENTIONED:

  • Metabolism Repair For Women, by Dr. Briden
  • Period Repair Manual (previous book)
  • Potential upcoming cookbook collaboration

  KEY TAKEAWAYS:

  1. Metabolism problems often come before weight gain, not after—it's about insulin resistance first
  2. Energy levels and satiety between meals are better indicators of metabolic health than body weight
  3. Environmental factors including toxins, processed oils, and gut dysfunction are major contributors to metabolic issues
  4. The body has a complex system that can't be micromanaged—focus on removing obstacles and supporting overall health
  5. Simple lab tests (ALT, triglycerides) can reveal insulin resistance more effectively than complex testing

  Website: https://www.larabriden.com/

  
  

  CALL TO ACTION:
  Subscribe to the One Thing Podcast for more conversations that challenge conventional health wisdom and center biology over blame. Share this episode with someone who's been struggling with metabolic health issues—these insights could be exactly what they need to hear.

After 6 years of hosting The One Thing Podcast and 20 years in clinical practice, I'm thrilled to announce my first group program: The Gut Freedom Intensive.

This is a 6-week cohort-based course that brings my one-on-one clinical approach to a small group format. If you've been struggling with IBS, SIBO, Inflammatory Bowel Disease, bloating, or any form of digestive distress, this intensive is designed for you.

What You'll Get:

• 6 weekly live group sessions with me
• Personalized roadmap for your specific digestive imbalances
• Deep dives into gut immunity, microbiome, food sensitivities, and more
• Interactive assignments to identify YOUR root causes
• Guidance on nutrition, lifestyle, supplements, and functional testing
• Ongoing support throughout the program

This isn't a one-size-fits-all approach. Through guided exercises and assessments, we'll uncover exactly what YOUR gut needs to heal.

Course Details:

• Starts: February 4th, 2026
• Duration: 6 weeks
• Format: Live weekly sessions + comprehensive curriculum
• Limited to 25 participants

Special Listener Discount: Listen to the special announcement where I mention a code that will give a discount of 20% off - good through December 15th, 2025

Enroll at: [Gut Freedom Intensive]

Questions? email support@soundintegrative.com

I look forward to guiding you on your journey to gut freedom.

Show Notes:🔗 Enroll in Gut Freedom Intensive: [LINK]📅 Course Starts: February 4, 2026

#guthealth #IBS #SIBO #digestivehealth #gutfreedom #functionalmedicine

In this episode, Dr. James Thompson, MD — a board-certified allergist, immunologist, author, and health educator — shares how a 21-day Daniel Fast sparked a life-changing shift toward plant-forward living. After 34 years in medicine, he realized that despite following what he believed was a “healthy” diet, he still required multiple long-term medications for blood pressure, cholesterol, and chronic inflammation. A plant-based lifestyle helped him eliminate medications, improve sleep and joint pain, and even restore vision.

Today, Dr. Thompson leads the Healthy Living With a Vision Foundation, delivering accessible nutrition and lifestyle medicine education to underserved communities. His FEARLESS Method (Food, Exercise, Avoid Toxins, Restorative Sleep, Less Stress, Engage Mind, Social Energy, Spirituality) is a practical roadmap for chronic disease prevention and sustainable health.

What You’ll Learn

• How fasting and plant-forward eating triggered Dr. Thompson’s health transformation

• Why medical education still provides minimal nutrition training

• How plants impact inflammation, cholesterol, metabolic health, and cognitive resilience

• The truth about protein needs and nutrient considerations (B12, omega-3s)

• How to start a plant-forward lifestyle without going “all or nothing”

• Health disparities in Black communities and why trust in healthcare remains fractured

• The FEARLESS Wellness pillars and how to apply them

Key TopicsPlant-forward nutrition · fasting · inflammation · lifestyle medicine · sleep · stress · chronic disease prevention · community health · spirituality · affordability

Time Stamps:

00:00 — Intro: Why nutrition conversations are polarized
01:30 — Meet Dr. James Thompson
03:11 — How the 21-day Daniel Fast changed everything
04:00 — Running, meds, and early health struggles
05:23 — The nutrition gap in medical training
07:20 — Diving into nutrition education
08:00 — Fasting & time-restricted eating
10:00 — How plant-forward living improved his health
11:20 — Greens, beans, berries & whole foods
12:21 — Unexpected vision improvements
14:29 — Defining plant-based vs. plant-forward
15:20 — Protein myths & amino acid basics
18:43 — How much protein you really need
20:44 — Key nutrients: B12 & omega-3s
24:26 — Getting omegas from plant foods
26:04 — Why patients trusted his holistic approach
29:51 — Introducing lifestyle medicine in practice
32:32 — Reversing chronic conditions through diet
34:29 — Planting seeds for long-term change
37:13 — Asthma, acne & inflammation stories
40:01 — Creating the FEARLESS Method
42:45 — The 8 FEARLESS pillars
45:16 — Starting small without overwhelm
48:25 — Working with the Black community
51:34 — Why medical mistrust persists
54:00 — COVID-19 & vulnerable populations
56:13 — The limits of access without education
57:03 — His current work & foundation
59:15 — What to buy with $5 for a healthy meal
1:00:50 — Spiritual frameworks for hard times
1:02:08 — Closing reflections

Notable Quotes“Within six months of going plant-based, I no longer needed blood pressure or cholesterol medication.”
“Doctors learn to diagnose and prescribe, not prevent.”

About Dr. James Thompson, MDDr. Thompson spent over three decades in allergy/immunology and internal medicine before shifting to lifestyle health education. His work focuses on plant-forward nutrition, chronic disease prevention, and equitable community wellness. His book FEARLESS Wellness outlines eight pillars for long-term vitality.

Website: FearlessMD21.com
Foundation: HealthyLivingWithAVision.org

You can spot a mouth breather from across the room — but what if that simple habit is reshaping your child’s face, disrupting their sleep, and setting the stage for autoimmune disease?
In this episode, Dr. Toni Ingram — biological dentist and founder of Flourish Dental Boutique in Dallas — joins us to uncover the powerful link between your mouth and your overall health.

We dive into:
• The truth about mouth breathing, nitric oxide, and cardiovascular protection
• How the oral microbiome drives inflammation and chronic illness
• Why dental plaque is a living biofilm — and what that means for disease risk
• Natural ways to strengthen teeth and rebalance your microbiome (no fluoride required)
• The oral clues behind poor sleep, ADHD-like symptoms, and immune dysfunction

Dr. Ingram reveals why your mouth is the gateway to your body — and how small daily practices like tongue scraping, xylitol sprays, and nasal breathing can transform your energy, sleep, and long-term health.

✨ Contest alert: Listen to the end for details on how to win an Oral DNA Microbiome Testing Kit!

Follow @drtonyingram on Instagram or visit flourishdentalboutique.com for more.

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Detailed Show Notes Found at: exclusive subtack page: https://adamrinde.substack.com/p/episode-127-dr-toni-engram-the-mouth

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