Featuring perspectives from Dr Jaffer A Ajani, Dr Samuel J Klempner, Dr Rutika Mehta and Dr John Strickler, moderated by Dr Klempner, including the following topics:

• Younger patient with metastatic HER2-positive, PD-L1-positive gastric cancer (0:00)
• Older patient with metastatic HER2-positive gastroesophageal (GE) cancer (8:13)
• Clinical applications for zanidatamab in GE cancer (13:58)

CME information and select publications

Featuring perspectives from Dr Paul G Richardson, including the following topics:

• Mechanism of action and pharmacology of cereblon E3 ligase modulators (0:00)
• Available efficacy data (4:54)
• Extramedullary disease (10:51)
• Side effects and toxicity (16:58)

CME information and select publications

Featuring an interview with Dr Hanny Al-Samkari, including the following topics:

• Case: A woman in her early 70s incidentally diagnosed with immune thrombocytopenia (ITP) experiences a suboptimal response to prednisone and IVIG — Bhavana (Tina) Bhatnagar, DO (0:00)
• Case: A man in his early 50s with a long history of ITP undergoes splenectomy — Neil Morganstein, MD (5:06)
• Case: A woman in her mid 50s with symptomatic iron-deficiency anemia who was found to have ITP has received corticosteroids, rituximab and IVIG — Jennifer Yannucci, MD (12:25)
• Case: A woman in her early 30s who previously received ABVD (doxorubicin/bleomycin/vinblastine/dacarbazine) and autologous stem cell transplant for Hodgkin lymphoma is diagnosed with ITP 5 years later that is refractory to high-dose prednisone, IVIG and rituximab, then romiplostim — Priya Rudolph, MD, PhD (18:19)

CME information and select publications